Changes in Brain ATP during Hypoxia
نویسندگان
چکیده
منابع مشابه
Brain metabolic changes in young vs aged rats during hypoxia.
Brain energy state and glycolytic metabolites were measured in young (6 month) and aged (28 month) male rats under normoxic (70% nitrous oxide, 30% oxygen) or hypoxic (PaO2 = 25 mm Hg) test conditions. Hypoxic ischemia was induced in one cerebral hemisphere by ligation of one carotid artery. Under normoxic test conditions brain energy metabolite concentrations were similar between young and age...
متن کاملBrain Metabolic Changes in Young vs Aged Rats During Hypoxia
and neuropathology of cerebral "anoxic-ischemic" cell change. Arch Neurol 29: 367-374, 1973 20. Rice JE, Vannucci RC, Brierley JB: The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 9: 131-141, 1981 21. Salford LG, Plum F, Siesjo BK: Graded hypoxia-oligemia in rat brain. Arch Neurol 29: 227-233, 1973 22. Levine S: Anoxic ischemic encephalopathy in rats. Am J Pat...
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Sleep is one of the most pervasive biological phenomena, but one whose function remains elusive. Although many theories of function, indirect evidence, and even common sense suggest sleep is needed for an increase in brain energy, brain energy levels have not been directly measured with modern technology. We here report that ATP levels, the energy currency of brain cells, show a surge in the in...
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Myocardial ATP utilization and resynthesis during hypoxia and reoxygenation were studied in vivo as a function of maturation. Graded hypoxia was performed in newborn (NB; 4-10 days old, n = 6) and mature sheep (MAT; 30-60 days old, n = 6). Time-resolved 31P-nuclear magnetic resonance was used to monitor myocardial phosphates throughout hypoxia and to monitor reoxygenation concomitant with rate ...
متن کاملBrain lipid changes following hypoxia.
Brain Lipid Changes Following Hypoxia • Biochemical changes signaling irreversible damage in brain cells following hypoxia are incompletely understood. Disruption of membrane structure may play a role in this process. Lipids and long-chain fatty acids are important constituents of neural membranes and could serve as markers of membrane breakdown. The present study was undertaken to assess the b...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a734